• Warfarin dose capping avoided supratherapeutic INRs in hospitalized elderly

    on March 30th, 2018
    REPORTING FROM THSNA 2018 SAN DIEGO (FRONTLINE MEDICAL NEWS) – A simple intervention of initial warfarin dose capping in hospitalized patients aged 85 years and older led to significant reductions in supratherapeutic INRs without a significant change in length of stay, a single-center study showed[...]
  • Higher preconception blood pressure linked to pregnancy loss

    on March 30th, 2018
    FROM HYPERTENSION High preconception blood pressure is associated with a greater risk of pregnancy loss, according to analysis of data from a randomized clinical trial of aspirin and pregnancy outcomes. Researchers in the EAGeR (Effects of Aspirin on Gestational and Reproduction) trial analyzed data[...]
  • Balloon pulmonary angioplasty for CTEPH improves heart failure symptoms

    on March 30th, 2018
    REPORTING FROM CRT 2018 WASHINGTON (FRONTLINE MEDICAL NEWS) – Balloon pulmonary angioplasty provides meaningful improvements in functional capacity for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are not candidates for surgical pulmonary thromboendarterectomy, according[...]
  • Many VTE patients live in fear of the next event

    on March 29th, 2018
    REPORTING FROM THSNA 2018 SAN DIEGO (FRONTLINE MEDICAL NEWS) – An estimated 41% of patients who experienced a venous thromboembolism (VTE) fear another clot often or almost all the time. In addition, about 25% report abnormal levels of anxiety, and 12% have abnormal depression scores. Those are ke[...]
  • High-dose oral ibuprofen most effective for PDA closure

    on March 27th, 2018
    FROM JAMA High-dose oral ibuprofen may be most likely to result in closure of hemodynamically significant patent ductus arteriosus (PDA) in preterm infants, compared with other pharmacological treatments, according to results of a recent systematic review and meta-analysis. However, using placebo or[...]
  • Major message: Most heart failure is preventable

    on March 26th, 2018
    EXPERT ANALYSIS FROM THE ANNUAL CARDIOVASCULAR CONFERENCE AT SNOWMASS SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – More than 960,000 new cases of heart failure will occur in the United States this year – and most of them could have been prevented, Gregg C. Fonarow, MD, asserted at the Annual Cardi[...]
  • Drug coated balloons may match stents for small coronary lesions

    on March 25th, 2018
    REPORTING FROM CRT 2018 WASHINGTON (FRONTLINE MEDICAL NEWS) – For treating de novo coronary lesions in vessels smaller than 2.75 mm, drug coated balloon angioplasty is as safe and may be as effective as drug-eluting stents, according to a multicenter randomized trial presented as a late-breaker at[...]
  • Debris left after TAVR varies by device

    on March 25th, 2018
    AT CRT 2018 WASHINGTON (FRONTLINE MEDICAL NEWS) – All transcatheter aortic valve replacement devices generate debris into the bloodstream, including debris larger than 1 mm, but the amount of the debris differs between devices, according to a study based on collections from a cerebral embolic prot[...]
  • Statin use is uniformly low in adults with dyslipidemia disorders

    on March 25th, 2018
    FROM CIRCULATION Only half of adults with familial hypercholesterolemia are currently on statin therapy, with even fewer receiving a high-intensity statin, according to an analysis of data from the National Health and Nutrition Examination Survey. “We found that 0.47% of the adult U.S. population [...]
  • Top hospital heart failure performance translates to longer survival

    on March 24th, 2018
    REPORTING FROM ACC 2018 ORLANDO (FRONTLINE MEDICAL NEWS) – Hospitals in the first quartile of short-term performance in treating heart failure patients had higher long-term survival rates for those patients, based on data from 317 hospitals that participated in a voluntary quality improvement prog[...]
  • Takotsubo cardiomyopathy incidence, mortality on the rise

    on March 23rd, 2018
    REPORTING FROM CRT 2018 WASHINGTON (FRONTLINE MEDICAL NEWS) – Hospitalizations for Takotsubo cardiomyopathy (TCM), a condition that primarily affects postmenopausal women, have been rising steadily, along with rates of in-hospital mortality due to this condition, according to a study conducted wit[...]
  • VIDEO: PFO closure device 100% effective against future strokes

    on March 23rd, 2018
    REPORTING FROM ACC 18 ORLANDO (FRONTLINE MEDICAL NEWS) – Closing a patent foramen ovale reduced the incidence of stroke and other adverse events in patients at increased risk the DEFENSE-PRO trial. “The potential association between patent foramen ovale [PFO] and cryptogenic stroke has been a co[...]
  • Beware of polypharmacy in patients taking warfarin

    on March 20th, 2018
    REPORTING FROM THSNA 2018 SAN DIEGO (FRONTLINE MEDICAL NEWS) – The incidence of polypharmacy among patients on warfarin therapy appears to peak at age 75, with close to 10 concurrent active prescriptions on average, results from a single-center study showed. “Beware of polypharmacy with these pa[...]
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